Yes. Research shows that NR is well absorbed and contributes to higher NAD⁺ levels in various types of cells, such as skin cells, muscle cells and brain cells. This supports normal cell energy and other bodily functions.

At BRONN, ‘longevity’ refers to supporting a healthy lifestyle and maintaining vitality, energy and well-being as we age. It is not about preventing ageing or extending life, but about supporting normal bodily functions and quality of life in the longer term.

Nicotinamide riboside (NR) has been extensively studied in scientific research as a precursor to NAD⁺. Research shows that NR is well absorbed by the body and can contribute to higher NAD⁺ levels in various types of cells, such as skin cells, muscle cells and brain cells. This supports normal bodily functions and forms the basis for the development of BRONN supplements. BRONN supplements have been developed based on these scientific insights.

BRONN supplements contain nicotinamide riboside (NR), a precursor of NAD⁺, a molecule that plays a role in energy production in cells and supports normal body function. Regular use can help support vitality and energy in healthy adults, which is part of a healthy lifestyle as we age.

Essentially, yes. They support cellular energy, and depending on your lifestyle, health, and age, the need for this will vary. BRONN supplements will therefore be beneficial for everyone, but individual experiences may differ.
BRONN supplements are safe for adults, with the exception of pregnant and breastfeeding women.

The effect of NR can vary depending on the product, the dose and individual physiology:
• Long-term use: For effects related to cell energy, recovery and vitality, such as with supplements for healthy ageing, regular use for 1 to 3 months or longer is recommended before noticeable effects occur. We recommend continuing to use these products chronically.
• Immediate effects: With products such as CELL BOOSTER NR, you may experience a temporary increase in alertness or energy within 30 minutes due to the specific formulation of these products.

All three molecules are essential for cellular health and are closely related to NAD+.
• NR (Nicotinamide Riboside) and NMN (Nicotinamide Mononucleotide) are both precursors (forerunners). This means that they are ingested to be converted into NAD+ in the cell, with the aim of restoring declining NAD+ levels (often due to ageing).
• NADH (Nicotinamide Adenine Dinucleotide + Hydrogen) is the active, energy-carrying form of NAD+. After NAD+ has captured electrons and a hydrogen atom in the mitochondria, it becomes NADH. NADH then donates these electrons to fuel the production of ATP (cellular energy).
In short: NR and NMN are building blocks for increasing the supply of essential NAD+. NADH is the energy-rich form that is created in the cell and plays a direct role in the cell's energy factory.

Nicotinamide Riboside (NR) is a precursor of NAD+. As such, it acts as a building block that is efficiently converted into NAD+ by the body using the NRK enzyme (Nicotinamide Riboside Kinase).
With ageing, the recycling capacity of existing NAD+ decreases, leading to reduced availability. The production of new NAD+ from its precursor NR then becomes a crucial supply route.

Taking NAD⁺ or NADH is possible, but it makes little sense. These molecules are so large and charged that the body can only absorb 10 to 15% of them. Furthermore, they are unstable molecules and therefore sensitive to moisture, heat, stomach acid and enzymatic degradation.
NR is up to 2.6 times smaller, which means it is absorbed much more easily. This molecule is also more stable and less sensitive to enzymes, for example.

NAD⁺ is a vital coenzyme that plays a crucial role in energy production in literally every cell in your body. A deficiency (which occurs naturally as we age) affects the most fundamental cellular processes:
- Reduced energy production due to inefficient conversion of nutrients into usable energy. This is often experienced as reduced energy, chronic fatigue, and a decline in stamina and physical performance.
- NAD⁺ is the fuel for repair enzymes. The deficiency causes these enzymes to become less active. As a result, DNA damage is repaired less efficiently, which can lead to the accumulation of damaged cells and an increased risk of age-related diseases.
- Accelerated ageing and disease: low NAD⁺ levels contribute to many characteristics of ageing

There are three explanations for this:
1. Increased breakdown by enzymes:
The activity of NAD⁺-consuming enzymes, particularly CD38 (which destroys NAD⁺) and PARPs (which consume NAD⁺ for DNA repair), increases with age.
2. Reduced recycling capacity:
The efficiency of the salvage pathway—the main route for NAD⁺ regeneration and recycling—declines as the activity of the crucial enzyme NAMPT decreases with age.
3. Stimulation by inflammation:
Chronic, low-grade inflammation (inflammaging) stimulates the overexpression and activity of NAD⁺-degrading enzymes such as CD38, further accelerating its breakdown.

There are testing methods to measure the NAD⁺ content in your blood or body cells. However, these are expensive and complex, so they are only used in the context of scientific research.

NAD+ (Nicotinamide Adenine Dinucleotide) is the essential coenzyme found in every cell of your body. Think of it as the master fuel that powers energy production, repairs DNA and maintains a healthy metabolism. Because our natural NAD⁺ levels decline as we age, supporting them has become an important focus for maintaining vitality and well-being.